Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320060 | 0.78 | CA12 (0.52) | CA12CA1CA7CA14ATM | |
| SCHEMBL5711180 | 0.74 | SMN1; SMN2 (0.45) | CA12CA1CA7CA14ATM | |
| SCHEMBL8071398 | 0.74 | SMN1; SMN2 (0.45) | CA12CA1CA7CA14ATM | |
| SCHEMBL7091384 | 0.73 | MMP8 (0.46) | CA12CA1CA7CA14ATM | |
| SCHEMBL28134677 | 0.73 | PTPN1 (0.50) | CA12CA1CA7CA14ATM | |
| SCHEMBL28841486 | 0.73 | MMP8 (0.54) | CA12CA1CA7CA14ATM | |
| SCHEMBL6054543 | 0.71 | MMP8 (0.45) | CA12CA1CA7CA14ATM | |
| SCHEMBL28879399 | 0.71 | MMP8 (0.45) | CA12CA1CA7CA14ATM | |
| SCHEMBL3592585 | 0.70 | CA12 (0.48) | CA12CA1CA7CA14ATM | |
| SCHEMBL3592587 | 0.70 | CA12 (0.48) | CA12CA1CA7CA14ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847201-A | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 1998-12-08 | — | — | US | disclosed |