Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134677 | 0.85 | PTPN1 (0.50) | MMP8CA12CA1CA7CA14 | |
| SCHEMBL28841486 | 0.85 | MMP8 (0.54) | MMP8CA12CA1CA7CA14 | |
| SCHEMBL6777966 | 0.85 | FFAR1 (0.50) | CA12CA1CA7CA14HIF1A | |
| SCHEMBL25262349 | 0.84 | CA2 (0.44) | ALDH1A1LMNA | |
| SCHEMBL28879399 | 0.84 | MMP8 (0.45) | MMP8CA12CA1CA7CA14 | |
| SCHEMBL6054543 | 0.84 | MMP8 (0.45) | MMP8CA12CA1CA7CA14 | |
| SCHEMBL28308777 | 0.83 | MMP8 (0.47) | MMP8SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL293540 | 0.83 | MMP8 (0.51) | MMP8SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL7882532 | 0.82 | MMP8 (0.44) | MMP8CA12CA1CA7CA14 | |
| SCHEMBL5144292 | 0.82 | MMP8 (0.51) | MMP8CA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227477-A1 | COMPOUNDS FOR SENSING REACTIVE OXYGEN SPECIES AND METHODS FOR USING THE SAME | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230227477-A1 | COMPOUNDS FOR SENSING REACTIVE OXYGEN SPECIES AND METHODS FOR USING THE SAME | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2023-07-20 | — | — | US | disclosed |
| WO-2021262998-A1 | COMPOUNDS FOR SENSING REACTIVE OXYGEN SPECIES AND METHODS FOR USING THE SAME | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2021-12-30 | — | — | WO | disclosed |
| US-20030032671-A1 | Propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032671-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | MMP8 2601/4885CA12 4472/4885CA1 3791/4885 |
| US-20230227477-A1 | COMPOUNDS FOR SENSING REACTIVE OXYGEN SPECIES AND METHODS FOR USING THE SAME | ROS1, GPX4, NOX4 | MMP8 1642/4885CA12 314/4885CA1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.