SCHEMBL8710223

SCHEMBL8710223

CC(=O)Nc1ccc(O)cc1NC=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CA12 O43570 1/20 0.44
BRD4 O60885 1/20 0.44
NR1I2 O75469 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MB P02144 1/20 0.44
CYP1A1 P04798 1/20 0.44
CA3 P07451 1/20 0.44
CYP3A4 P08684 1/20 0.44
RARG P13631 1/20 0.44
TSHR P16473 1/20 0.44
ALOX5AP P20292 1/20 0.44
CA4 P22748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27382037 0.83 MAPT (0.43) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL14138815 0.78 ALDH1A1 (0.57) POLBNPC1RAB9AALDH1A1MEN1
SCHEMBL5196761 0.77 KDM5A (0.41) MAPTALDH1A1MEN1KMT2ACA12
SCHEMBL29180547 0.76 ALDH1A1 (0.50) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL29716471 0.76 LMNA (0.61) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL2896946 0.76 POLB (0.71) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL9799672 0.76 LMNA (0.61) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL5464068 0.74 CYP3A4 (0.53) POLBMAPTRAB9AALDH1A1MEN1
SCHEMBL31198186 0.74 ALDH1A1 (0.57) POLBMAPTNPC1RAB9AALDH1A1
SCHEMBL8016782 0.74 ALDH1A1 (0.57) POLBMAPTNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540854-B1 Preparation for promoting hair growth SANSHO SEIYAKU KK (JP) 1998-01-21 EP disclosed
US-5656264-A ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE SANSYO SEIYAKU CO., LTD. (JP) 1997-08-12 US disclosed