SCHEMBL9799672

SCHEMBL9799672

CC(=O)Nc1cc(O)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
POLB P06746 3/20 0.61
KDM4E B2RXH2 3/20 0.61
HDAC1 Q13547 2/20 0.61
APOBEC3A P31941 1/20 0.61
GFER P55789 1/20 0.61
APOBEC3G Q9HC16 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
PHPT1 Q9NRX4 1/20 0.61
MAPT P10636 3/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
ALDH1A1 P00352 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29716471 1.00 LMNA (0.61) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL28306908 0.91 KDM4E (0.53) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL2896946 0.83 POLB (0.71) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL13608493 0.83 HDAC1 (0.83) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL19427493 0.83 MEN1 (0.58) POLBCA12CA1CA2CA7
SCHEMBL8016782 0.82 ALDH1A1 (0.57) LMNAPOLBSMN1; SMN2MAPTNPC1
SCHEMBL1224549 0.82 KCNMA1 (0.62) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL11417747 0.82 SMN1; SMN2 (0.59) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL11138178 0.81 CA12 (0.48) LMNAPOLBKDM4EHDAC1APOBEC3A
SCHEMBL4414788 0.81 ALDH1A1 (0.51) LMNAPOLBKDM4EHDAC1APOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019780-A Polyimide, polyimide precursor, composition, and method for producing polyimide 富士胶片株式会社 2024-05-10 CN disclosed
US-20220151991-A1 SMALL MOLECULE GRB2 STABILIZERS FOR RAS MAP KINASE INHIBITION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-05-19 US disclosed
CN-109880098-B Polyarylethersulfone resin with amino as crosslinking group and crosslinked product thereof 江西金海新能源科技有限公司 2021-06-08 CN disclosed
CN-109880098-A A kind of polyaryl ether sulphone resin and its cross-linking products using amino as crosslinked group 江西金海新能源科技有限公司 2019-06-14 CN disclosed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
CN-103703417-B Photosensitive composite, original edition of lithographic printing plate, the manufacture method of polyurethane and polyurethane 富士胶片株式会社 2017-07-14 CN disclosed
US-20160318849-A1 Hydrogen Peroxide-Activated Compounds as Selective Anti-Cancer Therapeutics UNIVERSITY OF CINCINNATI 2016-11-03 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20100197869-A1 Aromatic hydrogenated polymers containing fluorine SOLVAY SOLEXIS S.P.A. (IT) 2010-08-05 US disclosed
US-20100069275-A1 Fluorinated lubricants SOLVAY SOLEXIS S.P.A. (IT) 2010-03-18 US disclosed
US-20090326154-A1 Additives for Halopolymers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-31 US disclosed
US-7629483-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-08 US disclosed
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives SOLVAY SOLEXIS S.P.A. (IT) 2008-08-14 US disclosed
US-7371900-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-05-13 US disclosed
US-7365229-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-04-29 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-5026731-A 2,5-dihydroxyalkanoyl anilides SCHERING CORPORATION (US) 1991-06-25 US disclosed
US-4345019-A Diffusion transfer process MITSUBISHI PAPER MILLS, LTD. (JP) 1982-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318849-A1 Hydrogen Peroxide-Activated Compounds as Selective Anti-Cancer Therapeutics ROS1, GPX4, GPX1 LMNA 4043/4885POLB 252/4885KDM4E 3873/4885
US-20220151991-A1 SMALL MOLECULE GRB2 STABILIZERS FOR RAS MAP KINASE INHIBITION GRB2, KRAS, HRAS LMNA 4184/4885POLB 3387/4885KDM4E 2747/4885
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives FOXO1, FOXM1, F12 LMNA 1051/4885POLB 897/4885KDM4E 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.