Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527696 | 0.90 | TBXAS1 (0.52) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL9530136 | 0.90 | ALDH1A1 (0.62) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL10407005 | 0.86 | ALDH1A1 (0.63) | KMT2ATBXAS1ALDH1A1MEN1MAPT | |
| SCHEMBL9528581 | 0.85 | TBXAS1 (0.59) | KMT2ALMNATBXAS1ALDH1A1MEN1 | |
| SCHEMBL10452205 | 0.85 | SMN1; SMN2 (0.49) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL9528365 | 0.84 | TBXAS1 (0.58) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL9532300 | 0.84 | TBXAS1 (0.57) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27649130 | 0.84 | SMN1; SMN2 (0.47) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL10406925 | 0.83 | TBXAS1 (0.51) | KMT2ALMNATDP1TBXAS1ALDH1A1 | |
| SCHEMBL9529664 | 0.83 | TBXAS1 (0.63) | KMT2ALMNATBXAS1ALDH1A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4099767-A | — | — | None | — | — | JP | disclosed |
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| CN-1097741-A | Pyridine derivate, Preparation Method And The Use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | CN | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| JP-H0499767-A | USE OF 3-BENZOYLPYRIDINE O-BENZYLOXIMES AS HERBICIDE | NIPPON BAYERAGROCHEM KK | 1992-03-31 | — | — | JP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |