Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710463 | 0.90 | KMT2A (0.56) | TBXAS1TBXA2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9528177 | 0.88 | ALDH1A1 (0.56) | TBXAS1TBXA2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9530136 | 0.87 | ALDH1A1 (0.62) | TBXAS1TBXA2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9529153 | 0.81 | TBXAS1 (0.53) | TBXAS1TBXA2RALDH1A1MAPTGLA | |
| SCHEMBL9530015 | 0.79 | KDM4E (0.57) | LMNAALDH1A1MAPTGAAHPGD | |
| SCHEMBL10406925 | 0.77 | TBXAS1 (0.51) | TBXAS1TBXA2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10407005 | 0.77 | ALDH1A1 (0.63) | TBXAS1TBXA2RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9528581 | 0.77 | TBXAS1 (0.59) | TBXAS1TBXA2RKMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8482821 | 0.77 | LMNA (0.54) | TSHRKMT2ALMNATDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8482819 | 0.77 | LMNA (0.54) | TSHRKMT2ALMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |