Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | TACR1 | P25103 | 1/20 | 0.62 |
| ▸ | TACR3 | P29371 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707891 | 0.91 | CHRM2 (0.62) | GRIN2BMAPK14HTTCHRM2TACR1 | |
| SCHEMBL1063370 | 0.88 | MEN1 (0.66) | GRIN2BMAPK14HTTCHRM2CYP2C9 | |
| SCHEMBL1083550 | 0.88 | MEN1 (0.60) | GRIN2BMAPK14HTTCHRM2CYP2C9 | |
| SCHEMBL8711840 | 0.87 | MEN1 (0.63) | GRIN2BMAPK14CYP2C9CYP2C19HTR2B | |
| SCHEMBL8707900 | 0.87 | MAPK14 (0.60) | GRIN2BMAPK14HTTCYP2C9CYP2C19 | |
| SCHEMBL8708970 | 0.87 | CYP2C9 (0.60) | GRIN2BMAPK14CHRM2CYP2C9CYP2C19 | |
| SCHEMBL8707313 | 0.87 | TPSAB1 (0.61) | GRIN2BMAPK14CYP2C9CYP2C19HTR2B | |
| SCHEMBL8707626 | 0.86 | TACR1 (0.61) | GRIN2BMAPK14HTTCHRM2TACR1 | |
| SCHEMBL8707640 | 0.84 | MEN1 (0.65) | MAPK14CHRM2CYP2C9CYP2C19HTR2B | |
| SCHEMBL8711792 | 0.83 | HTT (0.68) | GRIN2BHTTGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| WO-1998028292-A1 | NOVEL PIPERIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |