Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.64 |
| ▸ | TNF | P01375 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063370 | 0.85 | MEN1 (0.66) | HTTSMN1; SMN2ALDH1A1GRIN2BMEN1 | |
| SCHEMBL8575988 | 0.84 | TNFSF11 (0.70) | HTTSMN1; SMN2LMNATNFSF11TNF | |
| SCHEMBL8707313 | 0.84 | TPSAB1 (0.61) | MAPTGRIN2BMEN1KMT2A | |
| SCHEMBL8711840 | 0.84 | MEN1 (0.63) | ALDH1A1GRIN2BMEN1KMT2A | |
| SCHEMBL8707900 | 0.84 | MAPK14 (0.60) | HTTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8710480 | 0.83 | GRIN2B (0.71) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL2718531 | 0.81 | HTT (0.80) | HTTSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8707640 | 0.81 | MEN1 (0.65) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1063365 | 0.81 | MEN1 (0.66) | HTTSMN1; SMN2ALDH1A1GRIN2BMEN1 | |
| SCHEMBL4810027 | 0.79 | GRIN2D (0.73) | HTTSMN1; SMN2LMNAMAPTGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028292-A1 | NOVEL PIPERIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |