Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063370 | 0.88 | MEN1 (0.66) | MEN1KMT2AMAPK14CYP2C9CYP2C19 | |
| SCHEMBL8707900 | 0.87 | MAPK14 (0.60) | MEN1KMT2AMAPK14CYP2C9CYP2C19 | |
| SCHEMBL8707313 | 0.87 | TPSAB1 (0.61) | MEN1KMT2AMAPK14CYP2C9CYP2C19 | |
| SCHEMBL8707891 | 0.87 | CHRM2 (0.62) | MAPK14CYP2C9CYP2C19GRIN2B | |
| SCHEMBL8710480 | 0.87 | GRIN2B (0.71) | MAPK14CYP2C9CYP2C19HTR2BGRIN2B | |
| SCHEMBL14357711 | 0.85 | MAPK14 (0.59) | MEN1KMT2AMAPK14 | |
| SCHEMBL8707640 | 0.85 | MEN1 (0.65) | MEN1KMT2AMAPK14CYP2C9CYP2C19 | |
| SCHEMBL1063365 | 0.84 | MEN1 (0.66) | MEN1KMT2AGRIN2BALDH1A1 | |
| SCHEMBL8711792 | 0.84 | HTT (0.68) | MEN1KMT2AGRIN2BALDH1A1 | |
| SCHEMBL14337827 | 0.83 | MEN1 (0.66) | MEN1KMT2AMAPK14CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028292-A1 | NOVEL PIPERIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |