Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18931745 | 0.86 | SCN10A (0.45) | SCN10AHDAC6KCNH2KIF11 | |
| SCHEMBL9304989 | 0.80 | SHBG (0.39) | SCN10AHDAC6KCNH2MAPT | |
| SCHEMBL711944 | 0.79 | NPBWR1 (0.43) | SCN10AKCNH2KIF11 | |
| SCHEMBL10852558 | 0.75 | HRH4 (0.41) | MAPTHSD17B10 | |
| SCHEMBL2339325 | 0.75 | — | — | |
| SCHEMBL10847755 | 0.73 | ALPL (0.35) | MAPTHSD17B10KIF11 | |
| SCHEMBL10844615 | 0.73 | KDM4E (0.41) | MAPTKIF11 | |
| SCHEMBL10579199 | 0.73 | — | — | |
| SCHEMBL229607 | 0.73 | KMT2A (0.44) | GAAMAPTHSD17B10 | |
| SCHEMBL482225 | 0.73 | F7 (0.44) | MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |