Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.75 |
| ▸ | DRD2 | P14416 | 10/20 | 0.75 |
| ▸ | DRD4 | P21917 | 10/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706525 | 0.92 | CCR3 (0.73) | CCR3DRD2DRD4SIGMAR1POLB | |
| SCHEMBL8706527 | 0.90 | DRD4 (0.74) | CCR3DRD2DRD4SLC6A12POLB | |
| SCHEMBL8706275 | 0.90 | DRD2 (0.65) | CCR3DRD2DRD4SIGMAR1POLB | |
| SCHEMBL8705987 | 0.89 | CCR3 (0.75) | CCR3DRD2DRD4SIGMAR1HTR2A | |
| SCHEMBL8712704 | 0.88 | DRD2 (0.76) | CCR3DRD2DRD4SIGMAR1POLB | |
| SCHEMBL18841068 | 0.86 | CCR3 (1.00) | CCR3MCHR1 | |
| SCHEMBL18841072 | 0.86 | CCR3 (1.00) | CCR3MCHR1 | |
| SCHEMBL8711087 | 0.86 | DRD2 (1.00) | CCR3DRD2DRD4SIGMAR1SLC6A12 | |
| SCHEMBL7239441 | 0.85 | CCR3 (0.72) | CCR3DRD4SIGMAR1SLC6A12TMEM97 | |
| SCHEMBL13580486 | 0.84 | CCR3 (0.67) | CCR3DRD4SIGMAR1SLC6A12TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037064-A1 | BENZAMIDES HAVING DOPAMINE D4 RECEPTOR AFFINITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-27 | — | — | WO | disclosed |