Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.76 |
| ▸ | DRD4 | P21917 | 13/20 | 0.76 |
| ▸ | CCR3 | P51677 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706525 | 0.90 | CCR3 (0.73) | DRD2DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL8706275 | 0.89 | DRD2 (0.65) | DRD2DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL8706527 | 0.89 | DRD4 (0.74) | DRD2DRD4CCR3POLB | |
| SCHEMBL8711089 | 0.88 | CCR3 (0.75) | DRD2DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL8712702 | 0.86 | DRD2 (1.00) | DRD2DRD4 | |
| SCHEMBL8711691 | 0.85 | DRD4 (0.74) | DRD2DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL7239441 | 0.84 | CCR3 (0.72) | DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL8705872 | 0.82 | DRD2 (0.73) | DRD2DRD4CCR3POLBSIGMAR1 | |
| SCHEMBL8711690 | 0.82 | DRD2 (1.00) | DRD2DRD4 | |
| SCHEMBL8705987 | 0.81 | CCR3 (0.75) | DRD2DRD4CCR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037064-A1 | BENZAMIDES HAVING DOPAMINE D4 RECEPTOR AFFINITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-27 | — | — | WO | disclosed |