Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.41 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711141 | 0.83 | ALOX5 (0.42) | ALOX5CYP1A2MAPTKDM4ECYP3A4 | |
| SCHEMBL1239542 | 0.81 | ALOX5 (0.65) | ALOX5LMNAMAPTALDH1A1CYP4Z1 | |
| SCHEMBL6771529 | 0.80 | CYP1A2 (0.63) | ALOX5CYP1A2CYP3A4SMN1; SMN2GAA | |
| SCHEMBL8848081 | 0.79 | CYP4Z1 (0.49) | ALOX5CYP1A2CYP3A4SMN1; SMN2GAA | |
| SCHEMBL12946405 | 0.78 | MAPT (0.68) | NPC1RAB9ACYP1A2LMNAMAPT | |
| SCHEMBL7999711 | 0.77 | ALOX5 (0.59) | ALOX5LMNAMAPTCYP4Z1CYP4F11 | |
| SCHEMBL8422184 | 0.76 | HDAC1 (0.58) | ALOX5CYP1A2GAACYP4Z1PPARG | |
| SCHEMBL3675681 | 0.76 | ALOX5 (0.57) | ALOX5LMNAMAPTCYP4Z1CYP4F11 | |
| SCHEMBL7831694 | 0.75 | HDAC1 (0.60) | ALOX5CYP1A2GAACYP4Z1PPARG | |
| SCHEMBL441220 | 0.74 | KDM4E (0.59) | ALOX5NPC1RAB9ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |