Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711145 | 0.83 | ALOX5 (0.45) | ALOX5CYP1A2MAPTHPGDCYP4Z1 | |
| SCHEMBL6771529 | 0.79 | CYP1A2 (0.63) | ALOX5CYP1A2FAAHCYP4Z1CYP4F11 | |
| SCHEMBL8422184 | 0.76 | HDAC1 (0.58) | ALOX5CYP1A2CYP4Z1CYP4F2CYP4A11 | |
| SCHEMBL7831694 | 0.75 | HDAC1 (0.60) | ALOX5CYP1A2CYP4Z1CYP4F2CYP4A11 | |
| SCHEMBL11733932 | 0.74 | LMNA (0.55) | CYP1A2CYP4Z1CYP4F11CYP4F12CYP3A4 | |
| SCHEMBL8848081 | 0.73 | CYP4Z1 (0.49) | ALOX5CYP1A2FAAHCYP4Z1CYP4F11 | |
| SCHEMBL2385413 | 0.71 | CYP4F2 (0.59) | CYP1A2MAPTCYP4Z1CYP4F2CYP4A11 | |
| SCHEMBL8889417 | 0.71 | TUBB4A (0.58) | ALOX5CYP1A2TUBB4ATUBBTUBA3C | |
| SCHEMBL16673019 | 0.70 | CYP4F2 (0.62) | ALOX5CYP1A2HPGDALDH1A1CYP4F2 | |
| Hydrochloric Acid SCHEMBL6981818 | 0.70 | TNF (0.49) | ALOX5HPGDCYP4Z1CYP4F11CYP4F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |