Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710951 | 0.90 | SLC18A3 (0.50) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8710844 | 0.90 | SLC18A3 (0.48) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8713817 | 0.89 | MEN1 (0.49) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8711156 | 0.88 | SLC18A3 (0.47) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8711236 | 0.87 | SLC18A3 (0.47) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8710852 | 0.87 | HSD11B1 (0.51) | SLC18A3HSD11B1HTR2AHTR2CHTR7 | |
| SCHEMBL8712075 | 0.87 | KCNH2 (0.51) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8714728 | 0.86 | SMN1; SMN2 (0.48) | SLC18A3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8711050 | 0.85 | SLC18A3 (0.44) | SLC18A3HTR2AHTR2CKDM4ECYP1A2 | |
| SCHEMBL8711207 | 0.85 | LMNA (0.49) | SLC18A3HTR2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |