Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708285 | 0.85 | MAPT (0.30) | ALDH1A1MAPT | |
| SCHEMBL8708141 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTPOLBNPSR1TDP1 | |
| SCHEMBL8708108 | 0.77 | KMT2A (0.39) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL9787804 | 0.76 | CTSL (0.37) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL9101106 | 0.71 | ACE (0.37) | — | |
| SCHEMBL8894255 | 0.69 | — | — | |
| SCHEMBL8893379 | 0.67 | — | — | |
| SCHEMBL7475849 | 0.67 | BACE1 (0.37) | — | |
| SCHEMBL6224857 | 0.67 | MAPT (0.48) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL7367580 | 0.67 | MAPT (0.48) | MEN1ALDH1A1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821222-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5529984-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |