Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.34 |
| ▸ | REN | P00797 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710905 | 0.88 | MMP1 (0.35) | CTSLCTSBCTSSCTSKBACE1 | |
| SCHEMBL9067940 | 0.78 | MMP1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8711405 | 0.78 | MEN1 (0.31) | ALDH1A1POLBMAPTNPSR1TDP1 | |
| SCHEMBL8713576 | 0.77 | CTSK (0.49) | ALDH1A1RENCTSLCTSBCTSS | |
| SCHEMBL9070551 | 0.76 | MMP1 (0.34) | ALDH1A1CTSLBACE1MMP1MMP3 | |
| SCHEMBL8895474 | 0.75 | MEN1 (0.43) | ALDH1A1CTSLCTSBCTSSCHRNB2 | |
| SCHEMBL8896038 | 0.75 | ALDH1A1 (0.34) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9073693 | 0.74 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8893220 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CTSLCTSBCTSSCHRNB2 | |
| SCHEMBL8894248 | 0.73 | ALDH1A1 (0.32) | ALDH1A1RENCTSKCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821222-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5529984-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |