Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | HTR7 | P34969 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8714632 | 0.99 | HTR1A (0.48) | HTR1AHTR7HTR6HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL8712886 | 0.83 | MAOB (0.50) | HTR1AHTR7HTR6MAOAMAOB | |
| Hydrochloric Acid SCHEMBL8899594 | 0.78 | HTR1A (0.43) | HTR1AHTR7HTR6HTR2ACYP19A1 | |
| SCHEMBL8714467 | 0.69 | CHRNA7 (0.48) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| SCHEMBL10226964 | 0.68 | MAOA (0.61) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL8711598 | 0.68 | CHRNA7 (0.47) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL8711956 | 0.68 | CHRNA7 (0.47) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL8718227 | 0.68 | CHRNA7 (0.47) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| SCHEMBL12608743 | 0.66 | MAOA (0.64) | HTR1AHTR7HTR6CYP19A1CYP11B1 | |
| SCHEMBL18235023 | 0.65 | CYP1A2 (0.58) | MAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |