Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712366 | 0.74 | MPO (0.46) | HPGDTSHRCNR2 | |
| SCHEMBL7058314 | 0.72 | MTNR1A (0.35) | HPGDTSHRCNR2ADRB3 | |
| SCHEMBL7055069 | 0.72 | MTNR1A (0.40) | CNR2 | |
| SCHEMBL8822773 | 0.69 | MTNR1A (0.35) | HPGDCNR2 | |
| SCHEMBL7056844 | 0.65 | MTNR1A (0.44) | HPGDTSHRADRB3 | |
| SCHEMBL8712370 | 0.59 | MTNR1A (0.44) | — | |
| SCHEMBL18525602 | 0.57 | MAOA (0.41) | HPGDTSHRCNR2 | |
| SCHEMBL7051614 | 0.56 | MTNR1A (0.65) | HPGD | |
| SCHEMBL14818597 | 0.56 | TP53 (0.38) | TSHR | |
| SCHEMBL2664618 | 0.56 | ESR1 (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |