Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707430 | 0.95 | SMN1; SMN2 (0.53) | HPGDSALDH1A1 | |
| SCHEMBL7869778 | 0.92 | HPGDS (0.48) | HPGDSCD274HPGD | |
| SCHEMBL8709459 | 0.88 | ADRA2A (0.51) | HPGDALDH1A1MAOAKCNH2 | |
| SCHEMBL8709099 | 0.86 | ADRA2A (0.49) | ALDH1A1MAOAKCNH2 | |
| SCHEMBL8708307 | 0.85 | ADRA2A (0.48) | ALDH1A1MAOAKCNH2 | |
| SCHEMBL8711424 | 0.84 | ADRA2A (0.47) | MAOAKCNH2 | |
| SCHEMBL8709047 | 0.84 | ADRA2A (0.47) | ALDH1A1MAOAKCNH2 | |
| SCHEMBL8708504 | 0.83 | ALDH1A1 (0.46) | HPGDALDH1A1MAOAKCNH2 | |
| SCHEMBL8711082 | 0.83 | ADRA2A (0.46) | HTR1AMAOAKCNH2 | |
| SCHEMBL8708441 | 0.82 | ADRA2A (0.49) | ALDH1A1MAOAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054140-A1 | NOVEL TEREPHTHALAMIDE DERIVATIVES | DONGWHA PHARMACEUTICAL IND. CO., LTD. (KR) | 1998-12-03 | — | — | WO | disclosed |