Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223043 | 0.74 | S1PR1 (0.32) | S1PR1S1PR3S1PR5 | |
| SCHEMBL8712184 | 0.70 | METAP1 (0.33) | SMN1; SMN2S1PR1S1PR3S1PR5 | |
| SCHEMBL23160555 | 0.66 | INPP5A (0.40) | SMN1; SMN2 | |
| SCHEMBL23160556 | 0.66 | INPP5A (0.40) | SMN1; SMN2 | |
| SCHEMBL18685936 | 0.65 | CACNA2D1 (0.37) | CACNA2D1CACNA1BCACNB1CACNA1CSMN1; SMN2 | |
| SCHEMBL8712186 | 0.64 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL7360357 | 0.63 | CACNA2D1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CSMN1; SMN2 | |
| SCHEMBL23707078 | 0.63 | CACNA2D1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CSMN1; SMN2 | |
| SCHEMBL6594713 | 0.63 | CACNA2D1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CSMN1; SMN2 | |
| SCHEMBL12423921 | 0.63 | CACNA2D1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |