Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL834319 | 0.91 | FFAR3 (0.72) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL4253065 | 0.88 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL5477656 | 0.88 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL8517702 | 0.88 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL315107 | 0.88 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL5904081 | 0.86 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9486329 | 0.86 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL7629511 | 0.85 | FFAR3 (0.72) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Cyclohexane SCHEMBL10429532 | 0.84 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL618898 | 0.84 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512162-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites and oligonucleotides | ASED, LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-9493773-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2016-11-15 | — | — | US | disclosed |
| US-20150252071-A1 | Synthesis of Deuterated Ribo Nucleosides, N-Protected Phosphoramidites and Oligonucleotides | ASED, LLC | 2015-09-10 | — | — | US | disclosed |
| US-9045521-B2 | Synthesis of deuterated ribo nucleosides N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20150119565-A1 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | ASED, LLC | 2015-04-30 | — | — | US | disclosed |
| US-8859754-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20140039175-A1 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC | 2014-02-06 | — | — | US | disclosed |
| US-5750666-A | FOR SYNTHESIZING NEW MONONUCLEOTIDES AND POLYNUCLEOTIDES HAVING PHOSPHOROTHIOATE AND PHOSPHORODITHIOATE INTERNUCLEOTIDE LINKAGES | COMPETITVE TECHNOLOGIES, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5684148-A | NUCLEOSIDES AND POLYNUCLEOTIDES AS FLUORESCENT AGENTS FOR MEDICAL DIAGNOSIS | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5602244-A | DINUCLEOSIDE PRECURSORS IN OLIGONUCLEOTIDE SYNTHESIS; USEFUL AS ANTISENSE INHIBITORS OF TRANSLATION | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5218103-A | Nucleoside thiophosphoramidites | UNIVERSITY PATENTS, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0378615-A4 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | — | 1992-04-08 | — | — | EP | disclosed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| US-4476301-A | Oligonucleotides, a process for preparing the same and their application as mediators of the action of interferon | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1984-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039175-A1 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | NSUN3, RNGTT, DUT | FFAR3 3252/4885HDAC3 1321/4885HDAC1 2575/4885 |
| US-20150252071-A1 | Synthesis of Deuterated Ribo Nucleosides, N-Protected Phosphoramidites and Oligonucleotides | NSUN3, DUT, RNGTT | FFAR3 3182/4885HDAC3 1167/4885HDAC1 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.