Butyric Acid

Butyric Acid

SCHEMBL618898

CCCC(=O)O.CCCCCC.CCN(CC)CC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.62
HDAC3 O15379 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC2 Q92769 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
AKR1B1 P15121 1/20 0.61
GPR84 Q9NQS5 7/20 0.58
PPARG P37231 7/20 0.58
PPARD Q03181 7/20 0.58
PPARA Q07869 7/20 0.58
HDAC11 Q96DB2 5/20 0.58
TSHR P16473 4/20 0.58
TDP1 Q9NUW8 4/20 0.58
PTPN1 P18031 3/20 0.58
ALDH1A1 P00352 3/20 0.58
KMT2A Q03164 3/20 0.58
TLR2 O60603 2/20 0.58
FABP4 P15090 2/20 0.58
MEN1 O00255 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL3485862 0.98 GPR84 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL2818571 0.98 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL834319 0.93 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8
Hexanoate SCHEMBL3411666 0.91 AKR1B1 (0.76) AKR1B1GPR84PPARGPPARDPPARA
Butyric Acid SCHEMBL5477656 0.90 FFAR3 (0.68) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8517702 0.90 FFAR3 (0.68) FFAR3HDAC3HDAC1HDAC2HDAC8
Heptanoate SCHEMBL3410001 0.88 GPR84 (0.77) AKR1B1GPR84PPARGPPARDPPARA
Decanoic Acid SCHEMBL5875269 0.88 GPR84 (0.77) AKR1B1GPR84PPARGPPARDPPARA
Octanoic Acid SCHEMBL3414554 0.88 GPR84 (0.77) AKR1B1GPR84PPARGPPARDPPARA
Undecanoate SCHEMBL21145218 0.88 GPR84 (0.77) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931431-B2 PSMA-targeted radiopharmaceutical for diagnosing and treating prostate cancer FUTURECHEM CO., LTD (KR) 2024-03-19 US disclosed
EP-3778592-B1 PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER FUTURECHEM CO LTD (KR) 2023-04-26 EP disclosed
US-20210106701-A1 PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER FUTURECHEM CO., LTD (KR) 2021-04-15 US disclosed
EP-3778592-A1 PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER Futurechem Co., Ltd. (KR) 2021-02-17 EP disclosed
EP-3604533-A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS Arbutus Biopharma Corporation (CA) 2020-02-05 EP disclosed
CN-106029675-B Pyridyl group diamino transition metal complex, its preparation and use 埃克森美孚化学专利公司 2019-11-19 CN disclosed
CN-109563110-A Quinolyl diamino transition metal complex, production and purposes 埃克森美孚化学专利公司 2019-04-02 CN disclosed
CN-104995196-B Biotin variants, streptavidin mutants and uses thereof 赛威德医疗公司 2018-10-12 CN disclosed
US-20180221494-A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-08-09 US disclosed
US-20180066009-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools CHEMGENES CORP (US) 2018-03-08 US disclosed
US-5091533-A Treating allergies, cardiovascular disorders, inflammation MERCK FROSST CANADA, INC. (CA) 1992-02-25 US disclosed
EP-0447189-A1 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors MERCK FROSST CANADA INC. (CA) 1991-09-18 EP disclosed
EP-0422889-A2 Phenethanolamine compounds GLAXO GROUP LIMITED (GB) 1991-04-17 EP disclosed
EP-0367576-A2 Estrogen nucleus derivatives for use in the inhibition of sex steroid activity ENDORECHERCHE INC. (CA) 1990-05-09 EP disclosed
EP-0227472-B1 10 BETA-ALKYNYLESTRENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.r.l. (IT) 1989-10-18 EP disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed
US-4808578-A ANTICARCINOGENIC AGENTS FARMITALIA CARLO ERBA S. R. L. (IT) 1989-02-28 US disclosed
US-4783483-A Epoxides useful as antiallergic agents ORTHO PHARMACEUTICAL CORPORATION (US) 1988-11-08 US disclosed
US-4670569-A 5-fluoro-PGI2 compounds G. D. SEARLE & CO. (US) 1987-06-02 US disclosed
US-4540801-A 5 Fluoro PGI compounds G. D. SEARLE & CO. (US) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11931431-B2 PSMA-targeted radiopharmaceutical for diagnosing and treating prostate cancer FOLH1, PSMA1, KLK3 FFAR3 2731/4885HDAC3 1762/4885HDAC1 982/4885
US-20180221494-A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS HAVCR2, LNPEP, BST2 FFAR3 3932/4885HDAC3 3547/4885HDAC1 4388/4885
US-20210106701-A1 PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER FOLH1, PSMA1, KLK3 FFAR3 2731/4885HDAC3 1762/4885HDAC1 982/4885
US-20180066009-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools UNG, OGG1, ADAR FFAR3 2932/4885HDAC3 4314/4885HDAC1 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.