Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714432 | 0.90 | HTR2C (0.49) | PDE4BQPCTPDE4APDE4CPDE4D | |
| SCHEMBL8712036 | 0.89 | RAB9A (0.54) | PDE4BQPCTPDE4APDE4CPDE4D | |
| SCHEMBL8713070 | 0.88 | PDE4B (0.43) | PDE4BQPCTPDE4APDE4CPDE4D | |
| SCHEMBL8710631 | 0.85 | PDE4B (0.49) | PDE4BQPCTPDE4APDE4CPDE4D | |
| SCHEMBL8711923 | 0.84 | QPCT (0.52) | QPCTNR1H2NR1H3RAB9A | |
| SCHEMBL8712205 | 0.78 | HTR2C (0.42) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8707085 | 0.78 | NR1H3 (0.46) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8713937 | 0.78 | PDE4B (0.47) | PDE4BQPCTPDE4APDE4CPDE4D | |
| SCHEMBL8707491 | 0.77 | HTR2C (0.49) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8713416 | 0.76 | HTR2C (0.42) | PDE4BPDE4APDE4CPDE4DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |