Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.73 |
| ▸ | MMP13 | P45452 | 15/20 | 0.73 |
| ▸ | MMP9 | P14780 | 13/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930656 | 0.89 | MMP1 (0.77) | MMP1MMP13MMP9ALDH1A1MMP2 | |
| SCHEMBL6928874 | 0.85 | MMP1 (1.00) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6932240 | 0.84 | MMP1 (0.69) | MMP1MMP13MMP9ALDH1A1MMP2 | |
| SCHEMBL6932190 | 0.82 | MMP9 (0.79) | MMP1MMP13MMP9MMP2MMP3 | |
| Diethylamine SCHEMBL7071575 | 0.81 | MMP13 (0.55) | MMP1MMP13MMP9ALDH1A1ADAM17 | |
| SCHEMBL7072864 | 0.80 | MMP1 (0.78) | MMP1MMP13MMP9ADAM17HTT | |
| SCHEMBL7071570 | 0.80 | MMP1 (0.78) | MMP1MMP13MMP9 | |
| SCHEMBL7072869 | 0.80 | MMP13 (0.56) | MMP1MMP13MMP9ALDH1A1ADAM17 | |
| SCHEMBL6932195 | 0.80 | MMP13 (0.63) | MMP1MMP13MMP9ALDH1A1MMP2 | |
| Diethylamine SCHEMBL7068261 | 0.80 | MMP9 (0.52) | MMP1MMP13MMP9ALDH1A1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847153-A | β-sulfonyl hydroxamic acids | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |