Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716354 | 1.00 | GRIN2B (0.44) | GRIN2BKCNJ5KCNJ3SLC6A2SLC6A4 | |
| SCHEMBL8713281 | 0.87 | PNMT (0.45) | PDE2AMC4RTP53HTR2AHTR2C | |
| SCHEMBL8713278 | 0.87 | PNMT (0.45) | PDE2AMC4RTP53HTR2AHTR2C | |
| SCHEMBL8713637 | 0.86 | HSD11B1 (0.36) | HSD11B1HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL8713634 | 0.86 | HSD11B1 (0.36) | HSD11B1HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL8716580 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2C | |
| SCHEMBL8716583 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2C | |
| SCHEMBL8713658 | 0.85 | LMNA (0.47) | SLC6A2SLC6A4SLC6A3HTR2AADRA2A | |
| SCHEMBL8713656 | 0.85 | LMNA (0.47) | SLC6A2SLC6A4SLC6A3HTR2AADRA2A | |
| SCHEMBL8716732 | 0.84 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |