Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713303 | 1.00 | PNMT (0.50) | PNMTSLC2A1ADRB1MIFHTR2A | |
| SCHEMBL8717066 | 0.88 | SLC2A1 (0.45) | PNMTSLC2A1ADRB1ADRA1ATRPM8 | |
| SCHEMBL8717068 | 0.88 | SLC2A1 (0.45) | PNMTSLC2A1ADRB1ADRA1ATRPM8 | |
| SCHEMBL8713862 | 0.88 | PNMT (0.50) | PNMTSLC2A1ADRB1ADRA1ATAAR1 | |
| SCHEMBL8713927 | 0.87 | ADRA2A (0.49) | ADRB1MIFHTR2AADRA1AHTR2B | |
| SCHEMBL8713926 | 0.87 | ADRA2A (0.49) | ADRB1MIFHTR2AADRA1AHTR2B | |
| SCHEMBL8713332 | 0.84 | TAAR1 (0.55) | PNMTSLC2A1ADRB1TAAR1ADRB3 | |
| SCHEMBL8713330 | 0.84 | TAAR1 (0.55) | PNMTSLC2A1ADRB1TAAR1ADRB3 | |
| SCHEMBL8716169 | 0.83 | SLC2A1 (0.45) | PNMTSLC2A1ADRB1ADRA1AADRB3 | |
| SCHEMBL8713871 | 0.83 | TAAR1 (0.47) | PNMTSLC2A1ADRB1MIFHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |