Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713926 | 1.00 | ADRA2A (0.49) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8713304 | 0.87 | PNMT (0.50) | LMNAHIF1AKDM4ETAAR1CYP2D6 | |
| SCHEMBL8713303 | 0.87 | PNMT (0.50) | LMNAHIF1AKDM4ETAAR1CYP2D6 | |
| SCHEMBL8714017 | 0.86 | CYP2D6 (0.58) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8714019 | 0.86 | CYP2D6 (0.58) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8716605 | 0.84 | LMNA (0.49) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8716602 | 0.84 | LMNA (0.49) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8720159 | 0.82 | TAAR1 (0.60) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8720156 | 0.82 | TAAR1 (0.60) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL8716247 | 0.79 | CYP2D6 (0.46) | ADRA2AADRA2CTAAR1CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |