Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713394 | 1.00 | CA2 (0.51) | CA2L3MBTL1MMP2MMP9ADAMTS4 | |
| SCHEMBL20906385 | 0.87 | MMP2 (0.58) | L3MBTL1MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL20906386 | 0.87 | MMP2 (0.58) | L3MBTL1MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL14812160 | 0.87 | MMP2 (0.58) | L3MBTL1MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL26619664 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MMP2MMP9ADAMTS4MEN1 | |
| SCHEMBL8716108 | 0.81 | CA2 (0.55) | CA2L3MBTL1MMP2MMP9ADAMTS4 | |
| SCHEMBL8716111 | 0.81 | CA2 (0.55) | CA2L3MBTL1MMP2MMP9ADAMTS4 | |
| SCHEMBL5230591 | 0.77 | CA2 (0.51) | CA2L3MBTL1MMP2MMP9ADAMTS4 | |
| SCHEMBL28038654 | 0.77 | CA2 (0.52) | CA2L3MBTL1MMP2MMP9ADAMTS4 | |
| SCHEMBL28038655 | 0.77 | CA2 (0.52) | CA2L3MBTL1MMP2MMP9ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |