Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717795 | 0.88 | F2 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8719757 | 0.86 | MAPT (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8716123 | 0.82 | ITGB3 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL11787863 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8715779 | 0.80 | F2 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8903964 | 0.79 | ITGB3 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8904649 | 0.78 | ITGB3 (0.53) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8718388 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7372766 | 0.77 | ITGB3 (0.67) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL8715797 | 0.77 | PIM1 (0.54) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |