Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | PLAU | P00749 | 5/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | PLAT | P00750 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712603 | 0.88 | NPC1 (0.48) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8712543 | 0.87 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8717795 | 0.85 | F2 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2ITGB3 | |
| SCHEMBL8716123 | 0.83 | ITGB3 (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8712984 | 0.78 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8713417 | 0.78 | KMT2A (0.48) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8712928 | 0.76 | CXCR1 (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8903332 | 0.74 | RAB9A (0.41) | ALDH1A1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL8712449 | 0.74 | RAB9A (0.41) | ALDH1A1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL8715779 | 0.74 | F2 (0.52) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |