Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741691 | 0.80 | SRD5A2 (0.41) | SRD5A1SRD5A2GRIN1GRIN2BMBOAT4 | |
| SCHEMBL8823339 | 0.79 | MBOAT4 (0.38) | SRD5A2MBOAT4 | |
| SCHEMBL8823337 | 0.79 | MBOAT4 (0.38) | SRD5A2MBOAT4 | |
| SCHEMBL8604667 | 0.79 | MBOAT4 (0.42) | GRIN1GRIN2BMBOAT4 | |
| SCHEMBL8158079 | 0.79 | SRD5A1 (0.42) | SRD5A1SRD5A2GRIN1GRIN2B | |
| SCHEMBL5596628 | 0.77 | SRD5A1 (0.54) | SRD5A1SRD5A2 | |
| SCHEMBL4729968 | 0.77 | SRD5A1 (0.54) | SRD5A1SRD5A2 | |
| SCHEMBL7617435 | 0.72 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL7617440 | 0.72 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL7711769 | 0.71 | MBOAT4 (0.38) | SRD5A1GRIN1GRIN2BMBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674521-A4 | METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17-g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5-g(a)-ANDROST-1-EN-3-ONES. | MERCK & CO INC (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0674521-A1 | METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17$g(b)-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5$g(a)-ANDROST-1-EN-3-ONES | MERCK & CO. INC. (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994015602-A1 | COMBINATION METHOD FOR TREATING PATTERNED ALOPECIA WITH 17β-N-SUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES AND MINOXIDIL | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994014452-A1 | METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17β-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES | MERCK & CO., INC. (US) | 1994-07-07 | — | — | WO | disclosed |