Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604667 | 0.80 | MBOAT4 (0.42) | MBOAT4GRIN1GRIN2BCDK5CDK5R1 | |
| SCHEMBL7741691 | 0.75 | SRD5A2 (0.41) | MBOAT4GRIN1GRIN2BSRD5A1 | |
| SCHEMBL7711773 | 0.74 | GRIN1 (0.40) | MBOAT4GRIN1GRIN2BCDK5CDK5R1 | |
| SCHEMBL27369735 | 0.74 | MBOAT4 (0.39) | MBOAT4GRIN1GRIN2BCDK5CDK5R1 | |
| SCHEMBL4729968 | 0.74 | SRD5A1 (0.54) | SRD5A1 | |
| SCHEMBL5596628 | 0.74 | SRD5A1 (0.54) | SRD5A1 | |
| SCHEMBL8528297 | 0.73 | HSD17B7 (0.42) | MBOAT4SRD5A1 | |
| SCHEMBL8713486 | 0.71 | SRD5A1 (0.41) | MBOAT4GRIN1GRIN2BSRD5A1 | |
| SCHEMBL7802581 | 0.71 | SRD5A1 (0.58) | SRD5A1 | |
| SCHEMBL7527164 | 0.71 | SRD5A1 (0.58) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365597-B1 | FOR THERAPY OF ANDROGEN AND ESTROGEN MEDIATED DISORDERS, INCLUDING BENIGN PROSTATIC HYPERPLASIA, ANDROGEN MEDIATED PROSTATE CANCER, ESTROGEN MEDIATED BREAST CANCER AND ACNE | AVENTIS PHARMACEUTICALS INC. | 2002-04-02 | — | — | US | disclosed |