Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminacrine SCHEMBL8711062 | 0.79 | ACHE (0.60) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL29354393 | 0.76 | HSD17B10 (1.00) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL14999 | 0.76 | HSD17B10 (1.00) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL28322757 | 0.75 | GAA (0.46) | ALDH1A1KDM4EKCNH2CASP1CASP7 | |
| Aminacrine SCHEMBL14482032 | 0.74 | HSD17B10 (0.95) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL31237441 | 0.74 | RAB9A (1.00) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL18989123 | 0.74 | HSD17B10 (0.95) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL30355377 | 0.74 | HSD17B10 (0.95) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL4907467 | 0.74 | HSD17B10 (0.95) | ACHEALDH1A1KDM4EHSD17B10HPGD | |
| Aminacrine SCHEMBL635597 | 0.74 | RAB9A (1.00) | ACHEALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057956-A1 | BIS(9-AMINOACRIDINE) DNA INTERCALATING AGENTS HAVING ANTITUMOR A ACTIVITY | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1998-12-23 | — | — | WO | disclosed |