Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21883574 | 0.93 | NOS2 (0.46) | NOS2NOS3SKP2TLR8KDM4E | |
| SCHEMBL21567686 | 0.89 | NOS2 (0.56) | NOS2NOS3TLR8LMNAKDM4E | |
| SCHEMBL7008513 | 0.81 | NOS2 (0.52) | NOS2NOS3SKP2TLR8GABRP | |
| SCHEMBL27839140 | 0.81 | NOS2 (0.43) | NOS2NOS3SKP2TLR8GABRP | |
| SCHEMBL11489975 | 0.80 | NOS2 (0.56) | NOS2NOS3LMNAKDM4EPOLB | |
| SCHEMBL28572387 | 0.78 | NOS2 (0.44) | NOS2NOS3SKP2TLR8GABRP | |
| Hexane SCHEMBL28173825 | 0.77 | NOS2 (0.52) | NOS2NOS3SKP2TLR8LMNA | |
| SCHEMBL19005863 | 0.76 | NOS2 (0.42) | NOS2NOS3LMNAKDM4ETDP1 | |
| SCHEMBL8713672 | 0.76 | NOS2 (0.82) | NOS2NOS3SKP2TLR8TLR7 | |
| SCHEMBL3836249 | 0.75 | TDP1 (0.40) | NOS2NOS3GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846720-A | Methods of determining chemicals that modulate expression of genes associated with cardiovascular disease | ONCOGENE SCIENCE, INC. (US) | 1998-12-08 | — | — | US | disclosed |