Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717846 | 0.91 | ALOX5AP (0.37) | PDE10ACYP1A2ALOX5AP | |
| SCHEMBL8714510 | 0.84 | PDE10A (0.39) | PDE10AMEN1MAPTKMT2AHCRTR1 | |
| SCHEMBL8717661 | 0.84 | HRH3 (0.36) | — | |
| SCHEMBL8714391 | 0.82 | PDE10A (0.38) | PDE10AMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL8713739 | 0.79 | OPRM1 (0.31) | — | |
| SCHEMBL9248655 | 0.77 | CYP1A2 (0.37) | PDE10ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8715302 | 0.77 | CYP1A2 (0.37) | PDE10ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8714480 | 0.77 | SLC18A2 (0.35) | MAPT | |
| SCHEMBL8714382 | 0.77 | CYP1A2 (0.36) | PDE10ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8717675 | 0.76 | GBA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |