Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713734 | 0.91 | PDE10A (0.39) | ALOX5APPDE10ACYP1A2 | |
| SCHEMBL8717311 | 0.82 | PDE10A (0.36) | ALOX5APCYSLTR1CYSLTR2PDE10ALGALS3 | |
| SCHEMBL8717767 | 0.82 | ALOX5AP (0.37) | ALOX5APCYSLTR1CYSLTR2PDE10ALGALS3 | |
| SCHEMBL8714480 | 0.82 | SLC18A2 (0.35) | — | |
| SCHEMBL8713739 | 0.80 | OPRM1 (0.31) | — | |
| SCHEMBL8717661 | 0.79 | HRH3 (0.36) | — | |
| SCHEMBL8717764 | 0.77 | BRD4 (0.36) | ALOX5APCYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL8714510 | 0.76 | PDE10A (0.39) | PDE10A | |
| SCHEMBL8715873 | 0.75 | CYSLTR1 (0.40) | ALOX5APCYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL9243625 | 0.75 | CYSLTR1 (0.40) | ALOX5APCYSLTR1CYSLTR2ALOX5GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |