Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713801 | 1.00 | LMNA (0.49) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8714017 | 0.90 | CYP2D6 (0.58) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8714019 | 0.90 | CYP2D6 (0.58) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8713318 | 0.88 | ALDH1A1 (0.52) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8713316 | 0.88 | ALDH1A1 (0.52) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8716602 | 0.88 | LMNA (0.49) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8714227 | 0.88 | TAAR1 (0.51) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8714224 | 0.88 | TAAR1 (0.51) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8716605 | 0.88 | LMNA (0.49) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8716601 | 0.84 | SLC6A4 (0.53) | LMNAADRA2AADRA2CHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |