SCHEMBL8713845

SCHEMBL8713845

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3ccc4ccccc4n3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.72
KDM4E B2RXH2 8/20 0.72
MAPT P10636 8/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
L3MBTL1 Q9Y468 3/20 0.72
MAPK1 P28482 3/20 0.72
RXFP1 Q9HBX9 1/20 0.72
NPC1 O15118 8/20 0.62
LMNA P02545 5/20 0.62
PKM P14618 2/20 0.62
SMN1; SMN2 Q16637 7/20 0.60
ALDH1A1 P00352 2/20 0.60
HTT P42858 3/20 0.53
GLA P06280 2/20 0.52
SLC2A1 P11166 1/20 0.50
CYSLTR2 Q9NS75 1/20 0.49
CYSLTR1 Q9Y271 1/20 0.49
HPGD P15428 2/20 0.48
NFKB1 P19838 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30708732 0.91 RAB9A (0.74) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL11022309 0.91 RAB9A (0.74) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL8822081 0.90 RAB9A (0.73) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL9617200 0.90 RAB9A (0.73) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL8822048 0.87 RAB9A (0.59) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL8822044 0.87 RAB9A (0.59) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL2394869 0.84 RAB9A (1.00) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL1348643 0.84 RAB9A (1.00) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL2494584 0.83 MAPT (0.72) RAB9AKDM4EMAPTMEN1KMT2A
SCHEMBL2494581 0.83 MAPT (0.72) RAB9AKDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10087627-A None JP disclosed
JP-H1087627-A TRIPHENYLAMINE DERIVATIVE HITACHI LTD 1998-04-07 JP disclosed
EP-0437310-B1 Photosensitive element for electrophotography HITACHI LTD (JP) 1997-03-26 EP disclosed
US-5215842-A With triphenylamine derivative as charge transport substance; sensitivity, image stability HITACHI, LTD. (JP) 1993-06-01 US disclosed
EP-0437310-A2 Photosensitive element for electrophotography HITACHI, LTD. (JP) 1991-07-17 EP disclosed