Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714091 | 1.00 | TAAR1 (0.38) | TAAR1DPP4DPP7ESR1ADRA2A | |
| SCHEMBL8716815 | 0.91 | TSHR (0.40) | TAAR1DPP4DPP7ALDH1A1GAA | |
| SCHEMBL8716819 | 0.91 | TSHR (0.40) | TAAR1DPP4DPP7ALDH1A1GAA | |
| SCHEMBL8715445 | 0.90 | TAAR1 (0.37) | TAAR1DPP4DPP7CYP3A4CYP2D6 | |
| SCHEMBL8715448 | 0.90 | TAAR1 (0.37) | TAAR1DPP4DPP7CYP3A4CYP2D6 | |
| SCHEMBL8714178 | 0.89 | KMT2A (0.39) | TAAR1ADRA2ACYP2D6 | |
| SCHEMBL8714177 | 0.89 | KMT2A (0.39) | TAAR1ADRA2ACYP2D6 | |
| SCHEMBL8714240 | 0.88 | SLC6A2 (0.43) | TAAR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8714237 | 0.88 | SLC6A2 (0.43) | TAAR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8716628 | 0.87 | IDO1 (0.41) | TAAR1ADRA2ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |