Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715448 | 1.00 | TAAR1 (0.37) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8714091 | 0.90 | TAAR1 (0.38) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8714092 | 0.90 | TAAR1 (0.38) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8716204 | 0.85 | SLC6A2 (0.44) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8716202 | 0.85 | SLC6A2 (0.44) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8716815 | 0.84 | TSHR (0.40) | TAAR1DPP4DPP7 | |
| SCHEMBL8716819 | 0.84 | TSHR (0.40) | TAAR1DPP4DPP7 | |
| SCHEMBL8714124 | 0.83 | CFD (0.40) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8714121 | 0.83 | CFD (0.40) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8720316 | 0.83 | SLC6A2 (0.48) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |