Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | DUSP22 | Q9NRW4 | 4/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10134069 | 0.90 | MEN1 (0.51) | MGLLDUSP22DUSP3MEN1KMT2A | |
| SCHEMBL10165555 | 0.80 | HSPD1 (0.51) | MGLLDUSP22DUSP3MEN1KMT2A | |
| SCHEMBL24487207 | 0.80 | KMT2A (0.56) | MGLLDUSP22DUSP3MEN1KMT2A | |
| SCHEMBL13873081 | 0.80 | KMT2A (0.50) | MGLLDUSP22MEN1KMT2AMAPT | |
| SCHEMBL8682649 | 0.79 | FFAR1 (0.47) | MEN1KMT2APOLBPTPN1MCL1 | |
| SCHEMBL8712071 | 0.78 | MGLL (0.50) | MGLLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8684983 | 0.78 | BCL2 (0.48) | DUSP22DUSP3MEN1KMT2APOLB | |
| SCHEMBL8711576 | 0.76 | MAPT (0.55) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL12081658 | 0.76 | MAPT (0.54) | MGLLDUSP22MEN1KMT2AMAPT | |
| SCHEMBL10134091 | 0.76 | DUSP22 (0.46) | DUSP22DUSP3MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716975-A | NONTOXIC RHODANINE DERIVATIVES; ANTIDIABETIC AGENTS, CATHEPSIN D INHIBITORS, B-AMYLOID PROTEIN REDUCTION | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |