SCHEMBL10165555

SCHEMBL10165555

C=C1SC(=S)N(c2ccc(O)cc2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPD1 P10809 1/20 0.51
HSPE1 P61604 1/20 0.51
MAPT P10636 6/20 0.50
KMT2A Q03164 6/20 0.50
MEN1 O00255 5/20 0.50
POLB P06746 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
ALOX12 P18054 1/20 0.50
MCL1 Q07820 2/20 0.49
BLM P54132 2/20 0.46
RECQL P46063 2/20 0.46
USP2 O75604 1/20 0.46
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24487207 0.83 KMT2A (0.56) MAPTKMT2AMEN1POLBALDH1A1
SCHEMBL13873081 0.83 KMT2A (0.50) MAPTKMT2AMEN1POLBKDM4E
SCHEMBL10134069 0.82 MEN1 (0.51) MAPTKMT2AMEN1POLBTDP1
SCHEMBL10134091 0.82 DUSP22 (0.46) HSPD1HSPE1MAPTKMT2AMEN1
SCHEMBL8714095 0.80 FAAH (0.47) MAPTKMT2AMEN1POLBTDP1
SCHEMBL8711576 0.79 MAPT (0.55) MAPTKMT2AMEN1POLBTDP1
SCHEMBL12081658 0.79 MAPT (0.54) MAPTKMT2AMEN1POLBALDH1A1
SCHEMBL20005600 0.78 SCN2A (0.50) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL20006080 0.76 DUSP22 (0.63) HSPD1HSPE1PKMDUSP22DUSP3
SCHEMBL8682797 0.76 BCL2 (0.43) MAPTKMT2AMEN1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258506-B2 Photoelectric conversion device, production method thereof and imaging device FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX HSPD1 2095/4885HSPE1 629/4885MAPT 342/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO HSPD1 4489/4885HSPE1 4276/4885MAPT 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.