Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714694 | 0.95 | ALDH1A1 (0.37) | MAPK1MEN1KMT2AGAACYP19A1 | |
| SCHEMBL8715839 | 0.93 | PTGS1 (0.37) | MAPK1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8719165 | 0.89 | MAPK1 (0.39) | MAPK1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL23556876 | 0.79 | SLC6A3 (0.41) | MAPK1MEN1KMT2ATP53SLC6A3 | |
| SCHEMBL8715017 | 0.78 | CHRM1 (0.32) | SLC6A3SLC6A2CHRM1SLC6A4MGAM | |
| SCHEMBL8720525 | 0.77 | MAPK1 (0.40) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8714043 | 0.76 | SLC6A3 (0.35) | MAPK1MEN1KMT2ATP53SLC6A3 | |
| SCHEMBL8714046 | 0.76 | SLC6A3 (0.35) | MAPK1MEN1KMT2ATP53SLC6A3 | |
| SCHEMBL13715018 | 0.74 | MAPK1 (0.58) | MAPK1MEN1KMT2A | |
| SCHEMBL5433093 | 0.74 | MAPK1 (0.58) | MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |