Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714046 | 1.00 | SLC6A3 (0.35) | SLC6A3SLC6A2CHRM1SLC6A4GNAI3 | |
| SCHEMBL8717806 | 0.95 | GNAI3 (0.40) | SLC6A3SLC6A2CHRM1SLC6A4GNAI3 | |
| SCHEMBL8714817 | 0.95 | GNAI3 (0.40) | SLC6A3SLC6A2CHRM1SLC6A4GNAI3 | |
| SCHEMBL8719610 | 0.93 | GNAI3 (0.42) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL11242228 | 0.93 | GNAI3 (0.42) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8719615 | 0.93 | GNAI3 (0.42) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8714425 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL8714421 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL4851968 | 0.82 | SLC6A3 (0.43) | SLC6A3SLC6A2CHRM1SLC6A4GNAI3 | |
| SCHEMBL11233388 | 0.81 | GBA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |