Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.63 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515542 | 0.78 | FDPS (1.00) | FDPSGGPS1LMNABTN3A1CA12 | |
| Water SCHEMBL28274320 | 0.76 | FDPS (0.96) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL3659339 | 0.76 | FDPS (0.71) | FDPSGGPS1LMNABTN3A1CA12 | |
| Methyl Alcohol SCHEMBL9715289 | 0.75 | FDPS (0.93) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL28199487 | 0.72 | FDPS (0.47) | FDPSGGPS1LMNABTN3A1CA12 | |
| Phosphonic Acid SCHEMBL10410285 | 0.71 | FDPS (0.63) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL5702824 | 0.71 | FDPS (0.63) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL28381527 | 0.70 | FDPS (0.76) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL9114540 | 0.70 | FDPS (0.61) | FDPSGGPS1LMNABTN3A1CA12 | |
| SCHEMBL28545484 | 0.70 | FDPS (0.45) | FDPSALDH1A1CYP19A1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1255501-A | Novel phosphonyl sulfonic ester compound and its medicinal compsns. | PROCTER & GAMBLE PHARMA (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1229083-A | Novel phosphononosulfonate compounds and its pharmaceutical compositions | PROCTER & GAMBLE PHARMA (US) | 1999-09-22 | — | — | CN | disclosed |
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5731299-A | OSTEOPOROSIS; RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| CN-1087640-A | Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | PROCTER & GAMBLE PHARMA (US) | 1994-06-08 | — | — | CN | disclosed |