Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.63 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659339 | 0.93 | FDPS (0.71) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL5702824 | 0.81 | FDPS (0.63) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL515542 | 0.78 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL5451506 | 0.77 | FDPS (0.58) | FDPSGGPS1BTN3A1CA12CA2 | |
| Water SCHEMBL28274320 | 0.76 | FDPS (0.96) | FDPSGGPS1BTN3A1CA12CA2 | |
| Methyl Alcohol SCHEMBL9715289 | 0.75 | FDPS (0.93) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL8714524 | 0.71 | FDPS (0.63) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL10247560 | 0.70 | AGER (0.62) | FDPSCYP19A1 | |
| SCHEMBL6692428 | 0.70 | — | — | |
| SCHEMBL9114540 | 0.70 | FDPS (0.61) | FDPSGGPS1BTN3A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939130-A | Substituted alkanediphosphonic acids and pharmaceutical use | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |