Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 7/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716933 | 0.79 | THRB (0.63) | THRBHTTMAPTKIF11AHR | |
| Hydrochloric Acid SCHEMBL8714082 | 0.78 | THRB (0.62) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8898840 | 0.77 | THRB (0.64) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8898835 | 0.77 | THRB (0.64) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8898838 | 0.77 | THRB (0.64) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8715349 | 0.71 | THRB (0.53) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8714061 | 0.70 | THRB (0.53) | THRBHTTMAPTKIF11KDM4E | |
| Hydrochloric Acid SCHEMBL8712061 | 0.69 | THRB (0.52) | THRBHTTMAPTKIF11KDM4E | |
| SCHEMBL8900776 | 0.69 | THRB (0.53) | THRBHTTMAPTKIF11AHR | |
| SCHEMBL8900764 | 0.69 | THRB (0.53) | THRBHTTMAPTKIF11AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |