Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KIF11 | P52732 | 6/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8714082 | 0.99 | THRB (0.62) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8715349 | 0.88 | THRB (0.53) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8714061 | 0.87 | THRB (0.53) | THRBHTTKIF11CTSVCTSL | |
| Hydrochloric Acid SCHEMBL8712061 | 0.86 | THRB (0.52) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8711566 | 0.85 | THRB (0.51) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8714601 | 0.85 | THRB (0.51) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8711631 | 0.81 | LMNA (0.43) | THRBHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL8714535 | 0.79 | THRB (0.41) | THRBHTTKIF11DRD3DRD2 | |
| SCHEMBL8248041 | 0.77 | HTT (1.00) | THRBHTTKIF11CTSVCTSL | |
| SCHEMBL8898607 | 0.77 | HTT (1.00) | THRBHTTKIF11CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | claimed |
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |