Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.43 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349300 | 0.80 | AVPR1A (0.51) | HSD11B1AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL7350019 | 0.75 | HSD11B1 (0.43) | HSD11B1AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL9838243 | 0.73 | AVPR2 (0.64) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL7356474 | 0.72 | AVPR1A (0.77) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL8558525 | 0.69 | AVPR1A (0.58) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL8719656 | 0.69 | AVPR2 (0.66) | AVPR1AAVPR2OXTR | |
| SCHEMBL8713003 | 0.69 | AVPR2 (0.58) | AVPR1AAVPR2OXTR | |
| SCHEMBL8715632 | 0.68 | AVPR2 (0.52) | AVPR1AAVPR2OXTR | |
| SCHEMBL6973320 | 0.66 | AVPR2 (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL8562670 | 0.66 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |